12,847

Research Papers

2,341

Clinical Trials

456

Active Studies

89

Meta-Analyses

1,200+

Researchers

Featured Research Studies

Clinical Trial

Cannabidiol for Treatment-Resistant Epilepsy: A Randomized Controlled Trial

📅 Published: January 2024 👥 Participants: 214 🏥 Phase III

This double-blind, placebo-controlled trial investigated CBD efficacy in patients with Dravet syndrome and Lennox-Gastaut syndrome who failed standard antiepileptic treatments.

Key Findings:

  • 43% reduction in seizure frequency vs. 27% in placebo group
  • 5% of patients achieved seizure freedom
  • Significant improvement in quality of life scores
  • Well-tolerated with manageable side effects
Read Full Study → Impact Score: 9.2
Meta-Analysis

Cannabis for Chronic Pain: Systematic Review of 32 Randomized Controlled Trials

📅 Published: November 2024 👥 Total Subjects: 5,174 📊 32 Studies

Comprehensive meta-analysis examining cannabis efficacy for neuropathic pain, fibromyalgia, rheumatoid arthritis, and cancer pain across multiple high-quality RCTs.

Key Findings:

  • 30% average pain reduction compared to placebo
  • Most effective for neuropathic pain (NNT: 6)
  • THC:CBD ratios of 1:1 showed best outcomes
  • Minimal serious adverse events reported
Read Full Study → Impact Score: 8.7
Systematic Review

CBD for Anxiety Disorders: Evidence from Clinical and Preclinical Studies

📅 Published: September 2024 📊 49 Studies Reviewed 🔬 Mixed Methods

Systematic review examining CBD's anxiolytic properties across generalized anxiety disorder, social anxiety disorder, PTSD, and panic disorder through human and animal studies.

Key Findings:

  • Significant anxiety reduction in 71% of studies
  • Optimal dosing range: 300-600mg for acute anxiety
  • No tolerance development observed
  • Superior to placebo for social anxiety disorder
Read Full Study → Impact Score: 8.1
Clinical Trial

THC:CBD Oromucosal Spray for Multiple Sclerosis Spasticity: 12-Month Follow-up

📅 Published: August 2024 👥 Participants: 337 🏥 Phase IV

Long-term efficacy and safety study of nabiximols (Sativex) in MS patients with moderate to severe spasticity resistant to standard treatments.

Key Findings:

  • 48% reduction in spasticity scores at 12 months
  • Improved sleep quality and bladder control
  • No significant tolerance to therapeutic effects
  • 76% of patients continued treatment after trial
Read Full Study → Impact Score: 8.5
Observational Study

Real-World Cannabis Use Patterns in Cancer Patients: Multi-Center Study

📅 Published: December 2024 👥 Participants: 1,842 🏥 18 Centers

Prospective observational study tracking cannabis use patterns, efficacy, and safety in cancer patients using medical cannabis for symptom management.

Key Findings:

  • 82% reported improved pain management
  • 74% experienced reduced nausea and vomiting
  • Significant appetite improvement in 68% of patients
  • Reduced opioid use in 47% of patients
Read Full Study → Impact Score: 7.9
Meta-Analysis

Cannabinoids and Sleep: Analysis of 34 Studies on Insomnia and Sleep Quality

📅 Published: October 2024 👥 Total Subjects: 3,891 📊 34 Studies

Meta-analysis examining various cannabinoid formulations for improving sleep onset, duration, and quality in patients with chronic insomnia and sleep disturbances.

Key Findings:

  • Average 36-minute reduction in sleep onset latency
  • CBN showed strongest sedative effects
  • THC:CBD (2:1) improved sleep maintenance
  • Minimal next-day cognitive impairment
Read Full Study → Impact Score: 7.6

Browse Research by Category

🧬

Neurology

Research on epilepsy, MS, Parkinson's, and other neurological conditions

847 Studies
💊

Pain Management

Clinical trials on chronic pain, neuropathic pain, and inflammation

1,234 Studies
🧠

Mental Health

Studies on anxiety, depression, PTSD, and mood disorders

623 Studies
🎗️

Oncology

Cancer symptom management and palliative care research

512 Studies
💤

Sleep Medicine

Research on insomnia, sleep quality, and circadian rhythms

289 Studies
🔬

Pharmacology

Cannabinoid mechanisms, pharmacokinetics, and drug interactions

1,456 Studies

Active Clinical Trials

Recruiting

CBD for Treatment of Anxiety in Adolescents

Phase: Phase II
Target Enrollment: 120 participants
Location: Multiple US Sites
Duration: 12 weeks

Purpose: To evaluate the efficacy and safety of oral CBD in adolescents (ages 13-17) with generalized anxiety disorder.

View Trial Details →
Active

Cannabis for Chemotherapy-Induced Peripheral Neuropathy

Phase: Phase III
Target Enrollment: 280 participants
Location: International
Duration: 24 weeks

Purpose: Randomized controlled trial comparing THC:CBD (1:1) to placebo for managing neuropathic pain in cancer patients.

View Trial Details →
Recruiting

CBG for Inflammatory Bowel Disease

Phase: Phase II
Target Enrollment: 60 participants
Location: Europe & Canada
Duration: 16 weeks

Purpose: To assess CBG efficacy in reducing inflammation and symptoms in patients with Crohn's disease and ulcerative colitis.

View Trial Details →
Completed

THCV for Type 2 Diabetes Management

Phase: Phase II
Enrollment: 62 participants
Location: UK
Duration: 13 weeks

Purpose: Evaluated THCV effects on glycemic control and insulin sensitivity in type 2 diabetes patients. Results published December 2024.

View Results →

Research Resources & Databases

📚 PubMed Cannabis Research

Access the complete database of cannabis and cannabinoid research indexed in PubMed/MEDLINE.

Search PubMed →

🔬 ClinicalTrials.gov

Browse ongoing and completed clinical trials on cannabis medicine worldwide.

View Trials →

📊 Cochrane Reviews

Systematic reviews and meta-analyses on cannabis for various medical conditions.

Read Reviews →

🎓 Research Guidelines

Methodological guidelines for conducting cannabis research and clinical trials.

View Guidelines →

📖 Journal Database

Curated list of peer-reviewed journals publishing cannabis research.

Browse Journals →

👨‍🔬 Researcher Directory

Connect with leading cannabis researchers and research institutions worldwide.

Find Researchers →

Submit Your Research

Are you conducting cannabis research? Share your findings with our community and contribute to the growing body of evidence.

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